Ye Cheng – Biomarker Imaging Approaches – Bioimaging Advances Award

Ye Cheng - Biomarker Imaging Approaches - Bioimaging Advances Award

Xuanwu Hospital Capital Medical University - China

AUTHOR PROFILE  

     SCOPUS

🎓 EARLY ACADEMIC PURSUITS

YE CHENG’s academic foundation is rooted in rigorous training, having honed his expertise at Harvard Medical School’s prestigious institutions, BWH and MGH. These formative years equipped him with advanced skills in neurosurgery and research. His commitment to neuroscience and targeted therapy began early, combining theoretical learning with practical mastery. This powerful combination laid the groundwork for his groundbreaking work in neuro-oncology. Now an Associate Professor, he uses his deep understanding of cortical structures and tumor biology to fuel a research career that bridges academia and medicine, setting him on a path to international scholarly recognition.

🧠 PROFESSIONAL ENDEAVORS

Currently serving as an Attending at Xuanwu Hospital, Capital Medical University, YE CHENG demonstrates an exceptional ability to integrate research with clinical application. His daily neurosurgical practice is informed by years of data-driven inquiry and innovative problem-solving. He has published extensively—over 20 articles in SCI-indexed journals—with work appearing in BMC Medicine and Cancer Letters. Cheng’s practical experience enhances his research authenticity, while his scientific expertise strengthens his role in complex surgeries. Through this synergy, he’s not just treating disease—he’s redefining the boundaries of what neurosurgeons can achieve in research-intensive clinical environments.

🔍 CONTRIBUTIONS AND RESEARCH FOCUS

YE CHENG’s research centers on the pathogenesis and treatment of central nervous system tumors. His pivotal discovery revealed that gliomas from different cortical regions carry varied prognoses due to underlying genetic differences. Published in Genes & Diseases, his findings link higher-order cortical development to tumor metabolism via ¹⁸F-FET PET imaging. This fusion of neuroevolution and oncology provides fresh insight into tumor behavior and paves the way for personalized treatments. Cheng's work highlights the significance of brain architecture in cancer development, laying a strong foundation for future research on neuro-tumor dynamics.

🧬 INNOVATION AND SCIENTIFIC ADVANCEMENT

YE CHENG’s research innovations extend beyond theories into impactful tools and technologies. He holds two authorized national invention patents, both rooted in his drive to improve diagnostic and surgical techniques. His interdisciplinary expertise bridges molecular imaging, neuroscience, and neurosurgery. By leveraging advanced radiopharmaceuticals, he introduced ¹⁸F-FET PET into tumor diagnostics, redefining how clinicians approach gliomas. This method helps identify tumor metabolism patterns and aligns treatment plans with tumor origin. Cheng’s integration of evolution, imaging, and genetics positions him at the forefront of translational neuro-oncology, pushing science toward more targeted and intelligent cancer care.

🏅 ACCOLADES AND RECOGNITION

YE CHENG’s achievements have been widely acknowledged, including the prestigious AANS/CNS Elekta Tumor Section Award. With nearly 1,000 citations and an H-index of 16, his scientific impact is evident and growing. His work is frequently published in high-impact journals and has collectively amassed an impact factor exceeding 100. These accolades underscore the academic community’s trust in his research. Cheng’s dual patents, numerous publications, and ongoing contributions mark him as a leader in neurosurgical innovation. His recognition reflects not just individual brilliance but a sustained dedication to advancing global standards in neuro-oncology.

🌐 IMPACT AND INFLUENCE

YE CHENG’s influence extends beyond the laboratory, shaping both patient care and scientific discourse. His novel insights into glioma behavior guide clinical decision-making and inspire fellow researchers to reexamine tumor biology through the lens of brain evolution. Internationally, his work has contributed to evolving diagnostic protocols, especially in integrating advanced imaging into surgical planning. As a mentor and collaborator, Cheng empowers emerging scientists, amplifying his impact through knowledge transfer. His contributions resonate through academic, clinical, and technological communities, ensuring that his research continues to influence the next generation of neuroscientists.

🔮 LEGACY AND FUTURE CONTRIBUTIONS

YE CHENG’s legacy is grounded in his vision for integrative, personalized neurosurgery. He aims to further explore the intersection of brain development and tumor growth, refining diagnostic imaging and targeted therapies. Plans for AI-assisted imaging diagnostics and expanded global collaborations signal a dynamic future. Cheng’s continued efforts promise not only technological breakthroughs but also more compassionate and effective treatments. By shaping the field’s evolution through inquiry, invention, and mentorship, he’s laying the groundwork for a future where brain tumors are better understood—and more precisely treated—than ever before.

Notable Publication

Title: Systematic pan-cancer analysis identifies DNASE2 as a potential prognostic marker and immunotherapeutic target for glioblastoma multiforme
Authors: J. Cao, S. Chen, P. An, S. Li, Y. Cheng
Journal: Genes and Diseases, 2025

Title: Cortical Origin-Dependent Metabolic and Molecular Heterogeneity in Gliomas: Insights from 18F-FET PET
Authors: H. Diao, X. Wu, X. Li, J. Lu, J. Tang
Journal: Biomedicines, 2025

Title: Inferring the genetic relationships between unsupervised deep learning-derived imaging phenotypes and glioblastoma through multi-omics approaches
Authors: L. Ye, Y. Cheng, P. Li, Y. Wang, W. Ma
Journal: Briefings in Bioinformatics, 2025

Xiang Xu – Cancer Biophotonics – Best Innovation Award

Xiang Xu - Cancer Biophotonics - Best Innovation Award

Amy Medical University of China - China

AUTHOR PROFILE

SCOPUS
ORCID

EARLY ACADEMIC PURSUITS 🎓

Professor Xiang Xu's journey in medical sciences began in China, where he displayed an early passion for cellular therapies and regenerative medicine. He earned his doctoral degree from the prestigious Third Military Medical University in 2006. His academic excellence and dedication to advancing medical research led him to pursue postdoctoral studies at Pittsburgh University from 2007 to 2009, where he explored the role of HDAC2 in promoting eIF4E sumoylation and activating mRNA translation gene specifically. These formative years laid the groundwork for his future breakthroughs in cytotherapeutics.

PROFESSIONAL ENDEAVORS 🌍

After completing his postdoctoral research, Professor Xu returned to China and became a principal investigator in the field of stem cell and regenerative medicine. In 2010, he joined the first department at the State Key Laboratory of Trauma, Burn, and Combined Injury, where he carried out groundbreaking research on cytotherapeutics. His leadership and expertise in the field positioned him as a pioneering figure in regenerative medicine.

CONTRIBUTIONS AND RESEARCH FOCUS 💡

Professor Xu has been at the forefront of developing innovative therapies in regenerative medicine. His research primarily focuses on immunocyte-based and stem cell-based therapies. In 2018, he founded the Department of Stem Cell & Regenerative Medicine at Daping Hospital of Amy Medical University, where he led multiple clinical and translational research projects. One of his most notable contributions is the development of a novel treatment strategy: the combination of human umbilical cord mesenchymal stem (stromal) cell transplantation with IFN-gamma treatment to improve clinical outcomes for patients with rheumatoid arthritis.

ACCOLADES AND RECOGNITION 🏆

Professor Xu’s pioneering research and contributions to cytotherapeutics have earned him widespread recognition. His work has been acknowledged in the scientific community through numerous awards and honors. As a distinguished professor at Amy Medical University, his influence extends beyond research, inspiring the next generation of scientists in stem cell therapy and regenerative medicine.

IMPACT AND INFLUENCE 👨‍🎓

Professor Xu's research has significantly influenced the field of regenerative medicine, particularly in the treatment of autoimmune diseases. His innovative therapeutic strategies have provided new hope for patients suffering from conditions such as rheumatoid arthritis. Through his leadership in academic and medical institutions, he has mentored numerous researchers and clinicians, further advancing the field of cytotherapeutics.

LEGACY AND FUTURE CONTRIBUTIONS ⚛️

\With a strong foundation in regenerative medicine, Professor Xu continues to push the boundaries of stem cell research. His legacy is defined by his commitment to translational research and clinical applications of cytotherapeutics. His future endeavors aim to refine stem cell-based treatments, explore new regenerative strategies, and expand the possibilities of cellular therapy for various medical conditions.

VISION FOR SCIENTIFIC ADVANCEMENT 🛠️

Professor Xu envisions a future where regenerative medicine and cytotherapeutics revolutionize healthcare. His continued efforts in stem cell research and immunotherapy aim to improve treatment outcomes for patients worldwide. Through his dedication to scientific progress, he is shaping a future where cell-based therapies become a cornerstone of modern medicine.

NOTABLE PUBLICATION

  • Title: Lactate-mediated lactylation in human health and diseases: Progress and remaining challenges
    Authors: Xue-ting Hu, Xiao-feng Wu, Jin-yi Xu, Xiang Xu
    Journal: Journal of Advanced Research

  • Title: The dual role of mesenchymal stem cells in apoptosis regulation
    Authors: Zhuo Chen, Xuewei Xia, Mengwei Yao, Yi Yang, Xiang Ao, Zhaoqi Zhang, Li Guo, Xiang Xu
    Journal: Cell Death & Disease

  • Title: XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial
    Authors: Qiu-Zhong Pan, Jing-Jing Zhao, Liang Liu, Dong-Sheng Zhang, Li-Ping Wang, Wen-Wei Hu, De-Sheng Weng, Xiang Xu, Yi-Zhuo Li, Yan Tang et al.
    Journal: Signal Transduction and Targeted Therapy

  • Title: Effect of GRK4 on renal gastrin receptor regulation in hypertension
    Authors: Xia, X.; Zeng, Y.; Li, Z.; Luo, H.; Wang, W.; He, Y.; Lu, B.; Guo, J.; Chen, K.; Xu, X.
    Journal: Clinical and Experimental Hypertension

  • Title: Fibulin2: a negative regulator of BMSC osteogenic differentiation in infected bone fracture healing
    Authors: Li, S.-D.; Xing, W.; Wang, S.-C.; Li, Y.-B.; Jiang, H.; Zheng, H.-X.; Li, X.-M.; Yang, J.; Guo, D.-B.; Xie, X.-Y. et al.
    Journal: Experimental and Molecular Medicine

  • Title: HGF Mediates Human Gingival Derived Mesenchymal Stem Cells Alleviated Airway Inflammation in Animal Models of Allergic Asthma
    Authors: Fang, Q.; Wu, W.; Xiao, Z.; Zeng, D.; Liang, R.; Wang, J.; Yuan, J.; Su, W.; Xu, X.; Zheng, Y. et al.
    Journal: SSRN