Mrs. Diana Reche | Novel Fluorescent Technologies | Best Researcher Award

PhD student at Pablo de Olavide University, Spain

Diana Reche López is a dedicated researcher specializing in rare and neurodegenerative diseases. She holds a Bachelor’s degree in Biology from the University of Seville and a Master’s degree in Health Biotechnology from Universidad Pablo de Olavide. Currently a Ph.D. student at the Andalusian Center for Developmental Biology, she is a key member of the PAIDI BIO-336 research group. Her work is focused on finding alternative treatments for KAT6B syndrome, a rare genetic disorder. With a strong foundation in molecular biology and cell culture techniques, Diana has contributed significantly to the field through numerous peer-reviewed publications and collaborations with esteemed scientists.

Profile

ORCID

Education:

Diana Reche López completed her Bachelor’s degree in Biology at the University of Seville (2013–2018), where she developed a deep interest in molecular biology and genetics. She then pursued a Master’s degree in Health Biotechnology at Universidad Pablo de Olavide (2018–2020), refining her expertise in experimental techniques and biomedical research. Currently, she is undertaking a Ph.D. in Biomedical Sciences at the same university, where her research focuses on cellular models for rare neurodegenerative disorders.

Experience:

As a doctoral researcher at the Andalusian Center for Developmental Biology, Diana has gained substantial expertise in cell culture techniques, immunofluorescence, quantitative PCR, Western Blot, lentivirus production, and in situ hybridization. Her extensive hands-on experience has allowed her to contribute significantly to multiple research projects on mitochondrial diseases and therapeutic interventions. She has also collaborated on various international studies, further strengthening her scientific impact and network.

Research Interest:

Diana’s primary research interests lie in the study of rare and neurodegenerative diseases. She focuses on understanding the molecular mechanisms underlying these conditions and identifying potential therapeutic strategies. Her work includes exploring the mitochondrial unfolded protein response (UPRmt) as a novel therapeutic target, investigating alternative treatment approaches for KAT6B syndrome, and utilizing patient-derived cellular models for precision medicine. She is passionate about advancing biomedical research to improve patient outcomes.

Awards:

Diana has been recognized for her contributions to biomedical research. She has been nominated for prestigious awards in the field of rare diseases and neurodegeneration. Her research excellence has been acknowledged through participation in funded projects, including a significant grant from the Instituto de Salud Carlos III for studying the modulation of UPRmt in mitochondrial diseases.

Publications:

“Therapeutic approach with commercial supplements for pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.”

• Álvarez-Córdoba, M., et al. (2022).  Orphanet Journal of Rare Diseases, 17(1), 311.
• Cited by: 164 articles.

“Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?”

• Suárez-Rivero, J. M., et al. (2022). Biomedicines, 10(7), 1611.
• Cited by: Multiple articles.

“Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration.”

• Villalón-García, I., et al. (2023).  Neural Regeneration Research, 18(6), 1196–1202.
• Cited by: Several studies.

“mtUPR Modulation as a Therapeutic Target for Primary and Secondary Mitochondrial Diseases.”

• Cilleros-Holgado, P., et al. (2023).  International Journal of Molecular Sciences, 24(2), 1482.
• Cited by: Notable journals.

“Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies.”

• Piñero-Pérez, R., et al. (2023).  Antioxidants, 12(12), 2023.
• Cited by: Various researchers.

“Biotin Induces Inactive Chromosome X Reactivation and Corrects Physiopathological Alterations in Beta-Propeller-Protein-Associated Neurodegeneration.”

• Reche-López, D., et al. (2025).  International Journal of Molecular Sciences, 26(3), 1315.
• Cited by: Leading studies.\

Conclusion:

Diana Reche López is a strong candidate for the Research for Best Researcher Award, particularly in biomedical research related to rare and neurodegenerative diseases. Her publication record, technical expertise, and involvement in significant research projects highlight her dedication to impactful scientific work. However, to further strengthen her profile, she could focus on leading independent research, increasing first-author publications, and expanding her scientific outreach.