Dr. Sang Bong Lee | SimVista Inc. | South Korea
Dr. Sang Bong Lee is a distinguished researcher in nuclear medicine, molecular imaging, and biophotonics, focusing on the development of theranostic nanoplatforms for cancer and inflammatory diseases. He has pioneered NMDAR-targeted imaging probes for tracking M1 macrophages and immune cells, enabling precise visualization of disease processes. His work on radionuclide-embedded gold and silica nanoparticles has advanced the field of molecular diagnostics and image-guided therapy. Dr. Lee has established bioadhesive orthotopic and metastatic colorectal cancer models that closely mimic human clinical conditions, providing improved platforms for translational research. He has innovated 4D-printed microrobot-based drug delivery systems that enhance targeted therapy and personalized medicine. His research integrates nanomedicine, molecular imaging, and advanced biomaterials to develop clinically relevant therapeutics. In addition, he leads the creation of cardiovascular and neurovascular intervention simulators, which combine physical vascular models, pulsatile pumps, and AI-enhanced virtual X-ray imaging to offer realistic, radiation-free training for interventional cardiologists and neurointerventionists. Dr. Lee’s work spans fundamental science to translational applications, bridging multidisciplinary fields including chemistry, medicine, engineering, and materials science. He has published extensively in SCI/SCIE-indexed journals and holds multiple patents in theranostic nanocomposites, microrobot systems, and simulation technologies. His research has introduced new approaches in immune-cell and platelet tracking, mesoporous silica and gold nanoparticle theranostics, and nanomaterial-based imaging probes. By integrating experimental innovation with clinical relevance, Dr. Lee has significantly advanced personalized and precision medicine. His contributions continue to influence molecular imaging, drug delivery, and medical training worldwide, setting benchmarks for innovation in biophotonics research. His work fosters collaboration across institutions, promoting the translation of laboratory discoveries into real-world healthcare solutions. Through his research, Dr. Lee has made a lasting impact on diagnostics, therapeutics, and advanced medical education, shaping the future of molecular imaging and biophotonics.
Profile: Google Scholar
Featured Publications
Lee, S. B., Kim, H. L., Jeong, H. J., Lim, S. T., Sohn, M. H., & Kim, D. W. (2013). Mesoporous silica nanoparticle pretargeting for PET imaging based on a rapid bioorthogonal reaction in a living body. Angewandte Chemie International Edition, 52(40), 203.
Nguyen, K. T., Go, G., Jin, Z., Darmawan, B. A., Yoo, A., Kim, S., Nan, M., & Lee, S. B., et al. (2021). A magnetically guided self-rolled microrobot for targeted drug delivery, real-time X-ray imaging, and microrobot retrieval. Advanced Healthcare Materials, 10(6), 2001681.
Sachin, K., Jadhav, V. H., Kim, E. M., Kim, H. L., Lee, S. B., Jeong, H. J., & Lim, S. T., et al. (2012). F-18 labeling protocol of peptides based on chemically orthogonal strain-promoted cycloaddition under physiologically friendly reaction conditions. Bioconjugate Chemistry, 23(8), 1680–1686.
Darmawan, B. A., Lee, S. B., Go, G., Nguyen, K. T., Lee, H. S., Minghui, N., & Hong, A., et al. (2020). Self-folded microrobot for active drug delivery and rapid ultrasound-triggered drug release. Sensors and Actuators B: Chemical, 128752, 75.