Biophysics at Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Russia
Dr. Nadezhda I. Fedotcheva is a distinguished researcher at the Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, in Pushchino, Russian Federation. Her contributions to biophysics, particularly in mitochondrial dysfunction, lipid peroxidation, and cellular mechanisms related to inflammation, have earned her a respected position in the scientific community. With over 70 published works and hundreds of citations, Dr. Fedotcheva’s research is recognized worldwide for its depth and impact.
Profile
Scopus
Strengths for the Award 💪
Dr. Fedotcheva’s work in mitochondrial dysfunction and cellular health addresses some of the most critical biomedical questions of our time. Her ability to investigate the intricate molecular mechanisms behind diseases such as inflammation and cancer distinguishes her from her peers.
With over 70 publications and an h-index of 15, her research is well-recognized and widely cited. This shows not only the quality of her work but also her influence in shaping current and future research in biophysics and related fields.
She has collaborated with a wide network of scientists and researchers globally, demonstrating her ability to work across disciplines. This collaboration is key in tackling complex scientific challenges and has led to several high-impact discoveries.
Dr. Fedotcheva has explored innovative ideas in the regulation of mitochondrial functions, including the use of bioactive molecules as potential therapeutic agents. Her focus on natural compounds and their impact on cellular health aligns with current trends in biomedical research, making her work highly relevant to the field.
Education 🎓
Dr. Fedotcheva received her education in biophysics and molecular biology from a renowned institution in Russia. She holds advanced degrees in biochemistry and experimental biology, which laid the foundation for her pioneering work in mitochondrial studies and cellular biophysics.
Experience 💼
With decades of research experience, Dr. Fedotcheva has held various positions at the Institute of Theoretical and Experimental Biophysics. Over her career, she has collaborated with numerous researchers globally, contributing to groundbreaking work in mitochondrial permeability transition and its implications for cellular health and disease. Her expertise spans from laboratory experiments to published theoretical analyses, making her a versatile and impactful scientist.
Research Interests 🔬
Dr. Fedotcheva’s research primarily focuses on mitochondrial biology, lipid peroxidation, and the study of bioactive compounds like acylcarnitines and microbial metabolites. She investigates how these elements affect cellular functions, particularly in contexts like inflammation, sepsis, and cancer. Her work on mitochondria explores the therapeutic potential of natural compounds in preventing diseases linked to mitochondrial dysfunction.
Awards 🏆
Dr. Fedotcheva has received recognition for her contributions to biophysics, although specific award information is not publicly available. She has been nominated multiple times for prestigious awards within the scientific community due to her outstanding contributions to understanding mitochondrial dysfunction and related cellular processes.
Publications 📚
Dr. Fedotcheva has authored and co-authored several influential research papers. Here are a few key publications:
Specific Features of Mitochondrial Dysfunction under Conditions of Ferroptosis Induced by t-Butylhydroperoxide and Iron: Protective Role of the Inhibitors of Lipid Peroxidation and Mitochondrial Permeability Transition Pore Opening
- Authors: Fedotcheva, T., Shimanovsky, N., Fedotcheva, N.
- Journal: Membranes
- Year: 2023
- Citations: 4
Involvement of the Mitochondrial Ca2+-Independent Phospholipase iPLA2 in the Induction of Mitochondrial Permeability Transition Pore by Long-Chain Acylcarnitines
- Authors: Fedotcheva, N.I., Grishina, E.V., Dynnik, V.V.
- Journal: Biologicheskie Membrany
- Year: 2023
- Citations: 0
Involvement of Multidrug Resistance Modulators in the Regulation of the Mitochondrial Permeability Transition Pore
- Authors: Fedotcheva, T., Shimanovsky, N., Fedotcheva, N.
- Journal: Membranes
- Year: 2022
- Citations: 5
Progesterone as an Anti-Inflammatory Drug and Immunomodulator: New Aspects in Hormonal Regulation of the Inflammation
- Authors: Fedotcheva, T.A., Fedotcheva, N.I., Shimanovsky, N.L.
- Journal: Biomolecules
- Year: 2022
- Citations: 44
Influence of Microbial Metabolites and Itaconic Acid Involved in Bacterial Inflammation on the Activity of Mitochondrial Enzymes and the Protective Role of Alkalization
- Authors: Fedotcheva, N., Beloborodova, N.
- Journal: International Journal of Molecular Sciences
- Year: 2022
- Citations: 6
Induction of Mitochondrial Cyclosporin-Dependent Permeability Transition Pore by Acylcarnitines. Effects of Concentrations and Carbon Chain Length
- Authors: Fedotcheva, N.I., Grishina, E.V., Dynnik, V.V.
- Journal: Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology
- Year: 2022
- Citations: 2
Induction of Mitochondrial Cyclosporin-dependent Permeability Transition Pore by Acylcarnitines. Effects of Concentrations and Carbon Chain Length
- Authors: Fedotcheva, N.I., Grishina, E.V., Dynnik, V.V.
- Journal: Biologicheskie Membrany
- Year: 2022
- Citations: 2
New Properties and Mitochondrial Targets of Polyphenol Agrimoniin as a Natural Anticancer and Preventive Agent
- Authors: Fedotcheva, T.A., Sheichenko, O.P., Fedotcheva, N.I.
- Journal: Pharmaceutics
- Year: 2021
- Citations: 8
Conclusion 🌍
Dr. Nadezhda I. Fedotcheva’s pioneering work in mitochondrial biology, combined with her scientific rigor and collaborative spirit, makes her an exceptional candidate for the Best Researcher Award. Her research is not only highly respected and cited but also has the potential to contribute to significant advancements in healthcare. While expanding the reach of her work and securing more formal recognition would strengthen her position, her current achievements alone make her a standout candidate deserving of this honor.